UMS Statisticians publish study on liver fibrosis for a NICE Guidance

UMS Statisticians, Dr Summers, Dr Douiri, Dr Wang, Dr Ayis, and Professor Peacock along with colleagues from Kings Technology Evaluation Centre (KiTEC) published this week in Applied Health Economics and Health Policy.

The study, as part of a NICE Medical Technology Guidance, investigated the use of Virtual Touch Quantification (VTR) to diagnose and monitor liver fibrosis in Hepatitis B and C.

In September 2015, NICE issued final guidance (MTG27) on this technology specifically in relation to liver fibrosis in patients with chronic hepatitis B or hepatitis C, and this study summarised this guidance and the evaluation process.

The study listed the following key points for decision makers:

  • Virtual Touch™ Quantification (VTq) is a software application used with Siemens Acuson ultrasound scanners to assess the stiffness of liver tissue and the stage of liver fibrosis.
  • The National Institute for Health and Care Excellence Medical Technology Evaluation Programme assessed the VTq software for use in people with hepatitis B or C and the External Assessment Centre estimated cost savings per patient for the VTq software in hepatitis patients was £53 when compared to transient elastography and £434 when compared to liver biopsy.
  • In September 2015, the VTq software was recommended for adoption within the National Health Service (NHS) for patients with hepatitis B or C for diagnosis and monitoring of liver fibrosis.