UMS members Odile Sauzet (associate) and Janet Peacock have published a study titled:
Binomial outcomes in dataset with some clusters of size two: can the dependence of twins be accounted for? A simulation study comparing the reliability of statistical methods based on a dataset of preterm infants
The study used stimulated data on a dataset of preterm infants to investigate ‘the performance of several approaches to the analysis of binomial outcomes in the presence of some clusters of size two’. The study found ‘that the number of covariates or the level two variance do not necessarily affect the performance of the various methods used to analyse datasets containing twins but when the percentage of small clusters is too small, mixed models cannot capture the dependence between siblings’.