UMS member Prof Peacock publishes in Cancer Prevention Research

Professor Janet Peacock & colleagues investigated the relationship between unmetabolized folic acid (UFA), tetrahydrofolate and colorectal adenoma risk.

The new study published in Cancer Prevention Research was an extension of the analysis of a previously published RCT. The new study, using post hoc analysis, found   that ‘during the later follow-up period in which folic acid supplementation was previously seen to increase the risk of advanced and multiple adenomas, higher serum methylated folates was associated with a higher risk of multiple and/or advanced adenomas, but no clear indication that UFA played a direct role’.